"Iktamuli" is a drawn animation film. A mother tells of her life with her son, who lives with trisomy 21, a so-called mental disability. Everyday scenes of mother and son drift into the mother's emotional world: rejection and sadness, but also joy and longing. For the mother, it is a great challenge to accept her son as he is. She can only change herself, the way she sees her son. "Iktamuli" tells of the conflict between motherly love and rejection, of the familiarity and strangeness between parents and children. The film scenes are assembled associatively. They follow the inner logic of the mother's experience, whose voice can be heard as an "inner monologue".